Hypericum perforatum, known as perforate St John’s-wort, common Saint John’s wort and St John’s wort is a flowering plant in the family Hypericaceae.
It is a medicinal herb with antidepressant activity and potent anti-inflammatory properties as an arachidonate 5-lipoxygenase inhibitor and COX-1 inhibitor.
Hypericum perforatum is native to parts of Europe and Asia.
St. John’s wort, similarly to other herbs, contains a whole host of different chemical constituents that may be pertinent to its therapeutic effects.
– St. John’s Wort has become popular again as an antidepressant. It is the number one treatment in Germany .
It contains several chemicals, including hypericin, hyperforin, and pseudohypericin, which are thought to be the major sources of antidepressant activity. – Neurotransmitters are chemicals that carry messages from nerve cells to other cells. Ordinarily, once the message has been delivered, neurotransmitters are re-absorbed and inactivated by the cells that released them. Chemicals in St. John’s wort may keep more of these antidepressant neurotransmitters available for the body to utilise. Multiple studies have shown that St. John’s wort may be effective in relieving mild to moderate depression, although maximum antidepressant effects may take several weeks to develop.
– Possible antiviral effects of St. John’s wort are being investigated for the treatment of HIV/AIDS, hepatitis C, and other viral illnesses. It is thought that hypericin, pseudohypericin, and other chemicals in St. John’s wort may stick to the surfaces of viruses and keep them from binding to host cells.
Another theory is that St. John’s wort may contain chemicals that interfere with the production or release of viral cells. This antiviral activity is enhanced greatly by exposure to light.